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    <pre style="white-space:pre-line"><code>Gli studi tribologici preliminari eseguiti pres-        3-319-14565-5 (eBook) DOI 10.1007/978-3-319-14565-5

so il Politecnico di Torino (prof. Costa) non           2.	 Francolini I, Donelli G (2010) Prevention and con-
hanno evidenziato alterazioni strutturali si-           trol of biofilm-based medical-device-related infections.
gnificative dopo la associazione con lo zinco           FEMS Immunol Med Microbiol 59(3):227â€“238
ione in entrambi i materiali polietilenici e di         3.	 Sousa C, Henriques M, Oliveira R (2011) Mini-re-
plastica medicale                                       view: antimicrobial central venous cath- etersâ€”recent
                                                        advances and strategies. Biofouling 27(6):609â€“620 

CONCLUSIONE                                             4.	 Costerton J, Stewart PS, Greenberg E (1999) Bacte-
                                                        rial biofilms: a common cause of persistent infections.
In pratica questi primi dati confermano che             Science 284(5418):1318â€“1322 

abbiamo evidenza di queste efficaci azioni              5.	 Welsh CA, Flanagan ME, Hoke SC, Doebbeling
antibatteriche sia sulle poliolefine cosÃ¬ co-           BN, Herwaldt L (2012) Reducing health care- associa-
me su tutte le catene polimeriche ramificate            ted infections (HAIs): lessons learned from a national
senza inficiarne le proprietÃ  chimico-fisiche.          collaborative of regional HAI programs. Am J Infect
Questo progetto medicale, applicabile a tutte           Control 40(1):29â€“34 

le specializzazioni di chirurgia (ortopedia,            6.	 Donlan RM (2001) Biofilm formation: a clinical-
neurochirurgia, chirurgia plastica, maxillo-            ly relevant microbiological process. Clin In- fect Dis
facciale ), puÃ² essere sottoposto a brevet-             33(8):1387â€“1392 

tazione, perchÃ© rappresenta un importante               7.	 Fanning S, Mitchell AP (2012) Fungal biofilms.
passo di prevenzione. Questa prevenzione so-            PLoS Pathog 8(4):e1002585 

prattutto sullâ€™inibizione della formazione di           8.	 2-Fey, P. D.; Olson, M. E. (2010). â€œCurrent con-
biofilm sulle superfici comprende una attiva            cepts in biofilm formation of Staphylococcus epidermi-
ricerca interdisciplinare, che deve coinvol-            disâ€. Future Microbiology. 5 (6): 917â€“933. doi:10.2217/
gere la collaborazione di medici, ingegneri,            fmb.10.56.
microbiologi e chimici. Per evitare le infezio-         9.	 ISO 22196. Second edition 2011.08.01_Internatio-
ni legati alla presenza di biofilm la strategia         nal Organization for Standardization
fondamentale Ã¨ quella di impedire lâ€™iniziale            10.	Sitografia:
fase di aderenza microbica e, quindi, la for-           11.	http://www.cdc.gov/hai/ Center for disease control,
mazione successive del biofilm, utilizzan-              cdc.gov.
do superfici con rivestimenti antimicrobici             12.	https://en.wikipedia.org/wiki/Staphylococcus_au-
(coating) o con lâ€™inclusione di sostanze ad             reus
attivitÃ  antimicrobica durante la produzione            13.	https://en.wikipedia.org/wiki/Staphylococcus_epi-
del materiale, destinato al medical device,             dermidis
biocompatibile perchÃ¨ deve integrarsi bene              14.	www.iss.it/pubblicazioni G. Donelli, I. Francolini,
con i tessuti ospitanti.                                V. Di Carlo, R. Di Rosa, F. Mastrilli, M. Antonelli, G.
                                                        Fadda, Protocollo per la prevenzione, diagnosi e tera-
BIBLIOGRAFIA                                            pia delle infezioni associate a cateteri venosi centrali.
                                                        (2002), iii, Rapporti ISTISAN 02/34
1.	 Hideyuki Kanematsu, Dana M. Barry Biofilm and
Materials Science Springer ISBN 978-3-319-14564-8 978-

                                                                                                                   59

                                                                                                                   032016</code></pre>
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